Conjugated linoleic acid (CLA): A study published in the Canadian Journal of Applied Physiology reported that CLA was one of only a few supplements researched and found to reduce body fat and assist in increasing lean muscle mass without a change in caloric intake. It seems CLA directs fats away from storage in fat cells while also increasing fat burning in the skeletal muscle. CLA is naturally present in dairy products and beef. It has also been found to have anticancer and antidiabetic properties and is useful in reducing arterial disease, potentially by affecting cholesterol levels. The dosage required is 1500 mg two times per day with food.
Hydroxycitric acid (HCA): HCA is derived from a fruit from India called Garcinia cambogia. Research has found that it helps to prevent the conversion of carbohydrates into fat by inhibiting an enzyme. The hormone insulin is a signal for fat storage; HCA helps reduce the secretion of insulin in response to glucose. HCA may also help reduce appetite.
Citrus aurantium: This is a natural stimulant derived from bitter orange. Unlike ephedra, which can have serious cardiovascular effects like increased pulse or blood pressure, auranticum is an effective fat-burning (thermogenic) and metabolic stimulant without negative consequences. It works by acting directly on the receptors of brown (thermogenic) and white (storage) fat cells to increase the breakdown of fat (lipolysis). Auranticum may also suppress hunger. The dosage required is an extract of 4% synephrine Citrus auranticum in a 500 mg capsule, 30 minutes before each meal three times per day.
Forskolin: Forskolin is obtained from the root of Coleus forskholii. Forskolin affects cell activity by stimulating an enzyme, cAMP, which acts as a messenger to regulate many vital cellular functions. Forskolin has many uses including treatment of asthma, high blood pressure, allergies and psoriasis as well as weight loss. Forskolin has been found to positively affect fat burning through the action on cAMP which increases the activity of fat-burning enzymes and stimulates metabolism by boosting thyroid function. Supplements of forskolin should be standardized to 4% and taken at 250 mg three times per day.