Summary of
Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem
contradictory. For clarification, read the full article for details about the summarized
interactions.
Avoid: Reduced drug absorption/bioavailability—Avoid these supplements
when taking this medication since the supplement may decrease the absorption and/or activity
of the medication in the body. |
Food
|
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Supportive interaction |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Foods and Other Compounds
Food
A study comparing the effect of a high-fat meal and a moderate-fat meal on the absorption of
vardenafil showed that taking the drug with a high-fat meal might result in a slight reduction
in effectiveness and a delayed onset of action up to one hour.1
References:1. Rajagopalan P, Mazzu A, Xia C, et al. Effect of high-fat breakfast and
moderate-fat evening meal on the pharmacokinetics of vardenafil, an oral phosphodiesterase-5
inhibitor for the treatment of erectile dysfunction. J Clin Pharmacol
2003;43:260–7.