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N-Acetyl-Glucosamine

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N-acetyl-glucosamine (NAG) is a form of glucosamine, one of the building blocks of joint tissue and other connective tissues. NAG differs from glucosamine sulfate and glucosamine hydrochloride; instead of a sulfur or chloride molecule, NAG has a larger, more complex molecule attached to it. As a result, NAG is an entirely different molecule than either glucosamine sulfate or hydrochloride, and it also appears to be handled by the body differently.

Where is it found?

NAG is available primarily in tablets and capsules.

Who is likely to be deficient?

As NAG is not an essential nutrient, no deficiency states have been reported.

How much is usually taken?

Most manufacturers recommend supplementation with 1,500 mg daily.

Are there any side effects or interactions?

No significant side effects or interactions have yet been reported in studies on NAG.

At the time of writing, there were no well-known drug interactions with N-acetyl-glucosamine.

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