Gamma oryzanol is a naturally occurring mixture of plant chemicals called sterols and
ferulic acid esters.
Where is it found?
Gamma oryzanol is a natural component of rice bran, corn, and barley oils. Gamma oryzanol is also
available as a supplement.
Gamma oryzanol has been
used in connection with the following condition (refer to the
individual health concern for complete information):
Who is likely to be deficient?
Since gamma oryzanol is not an essential nutrient, it is not associated with a deficiency
How much is usually taken?
Much of the human research with gamma oryzanol used 300 mg per day. Healthy people do not
appear to need this supplement.
Are there any side effects or interactions?
Some research suggests that gamma oryzanol taken in moderately high amounts (up to 600 mg
per day) for several months can cause dry mouth, sleepiness, hot flushes, irritability, and
light headedness in some individuals.1
At the time of writing, there were no well-known drug interactions
with gamma oryzanol.
1. 34. Takemoto T, Miyoshi H, Nagashima H. Clinical trial of Hi-Z fine
granules (gamma-oryzanol) on gastrointestinal symptoms at 375 hospitals (Japan). Shinyaku
To Rinsho 1977;26 [in Japanese].