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Butalbital

Combination drugs: Fioricet, Fiorinal, Phrenilin

Illustration

Butalbital is in a class of drugs known as barbiturates and is used to treat tension headaches. There are currently no reported nutrient or herb interactions involving butalbital. See barbiturates for interactions common to this class of drugs, though they have not yet been investigated for butalbital.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Avoid Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results.

Alcohol

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Foods and Other Compounds

Alcohol
Drinking alcoholic beverages while taking barbiturates increases side effects, such as drowsiness, confusion, and dizziness;1 2 if taken in excess, this combination may result in death. Consequently, people taking barbiturates should avoid drinking alcohol.

References:

1. Sifton DW, ed. Physicians Desk Reference, Montvale, NJ: Medical Economics Company, Inc., 2000, 906–7.

2. Olin BR, ed. Central Nervous System Drugs, Sedatives and Hypnotics, Barbiturates. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, 1993, 1398–413.

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