Bisoprolol is a beta-blocker drug used to lower blood pressure in people with hypertension.
Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem
contradictory. For clarification, read the full article for details about the summarized
Avoid: Adverse interaction—Avoid these supplements when taking this
medication because taking them together may cause undesirable or dangerous results.
|Depletion or interference
|Side effect reduction/prevention
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
Interactions with Dietary Supplements
Some beta-adrenergic blockers (called “nonselective” beta blockers) decrease the
uptake of potassium from the blood into the cells,1 leading to excess potassium in
the blood, a potentially dangerous condition known as hyperkalemia.2 People taking
beta-blockers should therefore avoid taking potassium supplements, or eating large quantities
of fruit (e.g., bananas), unless directed to do so by their
Interactions with Herbs
As pleurisy root and other plants in the Aesclepius species contain cardiac
glycosides, it is best to avoid use of pleurisy root with heart medications such as
Interactions with Foods and Other Compounds
Bisoprolol may be taken with or without food.4
Bisoprolol may cause drowsiness, dizziness, lightheadedness, or blurred vision.5
Alcohol may intensify these effects and increase the risk of accidental injury. To prevent
problems, people taking bisoprolol should avoid alcohol.
1. Rosa RM, Silva P, Young JB, et al. Adrenergic modulation of extrarenal
potassium disposal. N Engl J Med 1980;302:431–4.
2. Lundborg P. The effect of adrenergic blockade on potassium
concentrations in different conditions. Acta Med Scand Suppl 1983;672:121–6
3. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide
for Health-Care Professionals. London: Pharmaceutical Press, 1996, 213–4.
4. Leopold G, Pabst J, Ungethum W, Buhring KU. Basic pharmacokinetics of
bisoprolol, a new highly beta 1-selective adrenoceptor antagonist. J Clin Pharmacol
5. Threlkeld DS, ed. Diuretics and Cardiovasculars, Beta-Adrenergic
Blocking Agents. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and
Comparisons, Feb 1993, 158o.